PARP Inhibitor
PARP Inhibitor – It was announced today that PARP inhibitor or PARP inhibitor AZD2281 PARP inhibitors can help those with cancer.PARP inhibitor and chemotherapy (or any drug which damages DNA) work more effective for those who are ill.What is PARP inhibitor you may ask.Well here is the definition of PARP inhibitor:
A small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing, and antineoplastic activities. PARP inhibitor AZD2281 selectively binds to and inhibits PARP, inhibiting PARP-mediated repair of single strand DNA breaks; PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins and can be activated by single-stranded DNA breaks
That’s all we have for now on PARP Inhibitor.
Category: Health News
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